Probable Pitchers

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- 12:15pm EDT, Truist Park
- Athletics
- @
- Braves
- - Luis Severino (RHP)
  - 0–0, 3.60 ERA, 1.200 WHIP
  - Probable Catcher: Shea Langeliers
- - Chris Sale (LHP)
  - 1–0, 0.00 ERA, 1.000 WHIP
  - Probable Catcher: Drake Baldwin
- 12:35pm EDT, Oriole Park at Camden Yards
- Rangers
- @
- Orioles
- - Nathan Eovaldi (RHP)
  - 0–1, 9.64 ERA, 1.714 WHIP
  - Possible Catcher: Kyle Higashioka
- - Trevor Rogers (LHP)
  - 1–0, 0.00 ERA, 1.000 WHIP
  - Possible Catcher: Adley Rutschman
- 12:40pm EDT, Great American Ball Park
- Pirates
- @
- Reds
- - Paul Skenes (RHP)
  - 0–1, 67.50 ERA, 9.000 WHIP
  - Probable Catcher: Henry Davis
- - Andrew Abbott (LHP)
  - 0–0, 0.00 ERA, 1.333 WHIP
  - Probable Catcher: Tyler Stephenson
- 1:05pm EDT, Citizens Bank Park
- Nationals
- @
- Phillies
- - Cade Cavalli (RHP)
  - 0–0, 4.91 ERA, 1.636 WHIP
  - Possible Catcher: Keibert Ruiz
- - Cristopher Sánchez (LHP)
  - 1–0, 0.00 ERA, 0.500 WHIP
  - Probable Catcher: J.T. Realmuto
- 1:07pm EDT, Rogers Centre
- Rockies
- @
- Blue Jays
- - Kyle Freeland (LHP)
  - 0–1, 4.15 ERA, 1.615 WHIP
  - Probable Catcher: Hunter Goodman
- - Kevin Gausman (RHP)
  - 0–0, 1.50 ERA, 0.167 WHIP
  - Probable Catcher: Alejandro Kirk
- 1:10pm EDT, LoanDepot Park
- White Sox
- @
- Marlins
- - Shane Smith (RHP)
  - 0–1, 16.20 ERA, 3.000 WHIP
  - Possible Catcher: Edgar Quero
- - Sandy Alcantara (RHP)
  - 1–0, 0.00 ERA, 0.857 WHIP
  - Possible Catcher: Agustin Ramirez
- 1:15pm EDT, Busch Stadium
- Mets
- @
- Cardinals
- - Freddy Peralta (RHP)
  - 1–0, 7.20 ERA, 1.200 WHIP
  - Probable Catcher: Francisco Álvarez
- - Matthew Liberatore (LHP)
  - 0–0, 1.80 ERA, 1.800 WHIP
  - Probable Catcher: Pedro Pagés
- 1:40pm EDT, American Family Field
- Rays
- @
- Brewers
- - Drew Rasmussen (RHP)
  - 0–0, 1.80 ERA, 0.800 WHIP
  - Possible Catcher: Nick Fortes
- - Jacob Misiorowski (RHP)
  - 1–0, 1.80 ERA, 1.000 WHIP
  - Probable Catcher: William Contreras
- 2:10pm EDT, Daikin Park
- Red Sox
- @
- Astros
- - Garrett Crochet (LHP)
  - 1–0, 0.00 ERA, 0.833 WHIP
  - Probable Catcher: Carlos Narvaez
- - Mike Burrows (RHP)
  - 0–1, 7.94 ERA, 1.941 WHIP
  - Probable Catcher: Yainer Diaz
- 2:20pm EDT, Wrigley Field
- Angels
- @
- Cubs
- - Yusei Kikuchi (LHP)
  - 0–0, 4.15 ERA, 2.077 WHIP
  - Probable Catcher: Travis d'Arnaud
- - Matt Boyd (LHP)
  - 0–1, 14.73 ERA, 1.909 WHIP
  - Probable Catcher: Carson Kelly
- 3:40pm EDT, Chase Field
- Tigers
- @
- Diamondbacks
- - Tarik Skubal (LHP)
  - 1–0, 0.00 ERA, 0.500 WHIP
  - Probable Catcher: Dillon Dingler
- - Zac Gallen (RHP)
  - 0–1, 9.00 ERA, 1.750 WHIP
  - Probable Catcher: James McCann
- 4:10pm EDT, T-Mobile Park
- Yankees
- @
- Mariners
- - Cam Schlittler (RHP)
  - 1–0, 0.00 ERA, 0.188 WHIP
  - Probable Catcher: Austin Wells
- - George Kirby (RHP)
  - 1–0, 1.50 ERA, 0.667 WHIP
  - Probable Catcher: Cal Raleigh
- 4:10pm EDT, Petco Park
- Giants
- @
- Padres
- - Adrian Houser (RHP)
  - First appearance this season
  - Probable Catcher: Patrick Bailey
- - Nick Pivetta (RHP)
  - 0–1, 18.00 ERA, 3.333 WHIP
  - Probable Catcher: Freddy Fermin
- 7:40pm EDT, Kauffman Stadium
- Twins
- @
- Royals
- - Joe Ryan (RHP)
  - 0–0, 0.00 ERA, 0.563 WHIP
  - Possible Catcher: Ryan Jeffers
- - Noah Cameron (LHP)
  - First appearance this season
  - Possible Catcher: Salvador Perez
- 8:20pm EDT, Dodger Stadium
- Guardians
- @
- Dodgers
- - Gavin Williams (RHP)
  - 0–1, 5.40 ERA, 1.600 WHIP
  - Probable Catcher: Bo Naylor
- - Yoshinobu Yamamoto (RHP)
  - 1–0, 3.00 ERA, 0.833 WHIP
  - Probable Catcher: Will Smith

Probable Pitchers

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