Probable Pitchers

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- 9:40am PDT, Great American Ball Park
- Brewers
- @
- Reds
- - Colin Rea (RHP)
  - 12–4, 3.61 ERA, 1.155 WHIP
  - Probable Catcher: William Contreras
- - Nick Martinez (RHP)
  - 6–6, 3.62 ERA, 1.112 WHIP
  - Probable Catcher: Tyler Stephenson
- 3:40pm PDT, Citizens Bank Park
- Braves
- @
- Phillies
- - Reynaldo Lopez (RHP)
  - 7–4, 2.02 ERA, 1.184 WHIP
  - Probable Catcher: Sean Murphy
- - Ranger Suarez (LHP)
  - 11–5, 2.97 ERA, 1.062 WHIP
  - Probable Catcher: J.T. Realmuto
- 3:40pm PDT, Comerica Park
- Red Sox
- @
- Tigers
- - Tanner Houck (RHP)
  - 8–9, 3.29 ERA, 1.179 WHIP
  - Possible Catcher: Connor Wong
- - To Be Announced
- 3:40pm PDT, Great American Ball Park
- Brewers
- @
- Reds
- - To Be Announced
- - Rhett Lowder (RHP)
  - First appearance this season
  - Probable Catcher: Tyler Stephenson
- 3:45pm PDT, Nationals Park
- Cubs
- @
- Nationals
- - To Be Announced
- - Jake Irvin (RHP)
  - 9–10, 3.80 ERA, 1.158 WHIP
  - Probable Catcher: Keibert Ruiz
- 3:50pm PDT, Tropicana Field
- Padres
- @
- Rays
- - Martin Perez (LHP)
  - 3–5, 4.51 ERA, 1.505 WHIP
  - Possible Catcher: Kyle Higashioka
- - Taj Bradley (RHP)
  - 6–8, 3.77 ERA, 1.155 WHIP
  - Probable Catcher: Alex Jackson
- 4:05pm PDT, Yankee Stadium
- Cardinals
- @
- Yankees
- - Erick Fedde (RHP)
  - 8–7, 3.31 ERA, 1.165 WHIP
  - Possible Catcher: Pedro PagÃ©s
- - Marcus Stroman (RHP)
  - 9–6, 3.94 ERA, 1.398 WHIP
  - Possible Catcher: Jose Trevino
- 4:10pm PDT, Progressive Field
- Pirates
- @
- Guardians
- - Bailey Falter (LHP)
  - 6–7, 4.25 ERA, 1.264 WHIP
  - Possible Catcher: Joey Bart
- - Ben Lively (RHP)
  - 11–8, 3.62 ERA, 1.192 WHIP
  - Probable Catcher: Bo Naylor
- 5:05pm PDT, Globe Life Field
- Athletics
- @
- Rangers
- - JP Sears (LHP)
  - 10–9, 4.36 ERA, 1.210 WHIP
  - Probable Catcher: Shea Langeliers
- - Jon Gray (RHP)
  - 5–5, 4.13 ERA, 1.316 WHIP
  - Probable Catcher: Jonah Heim
- 5:10pm PDT, Minute Maid Park
- Royals
- @
- Astros
- - Seth Lugo (RHP)
  - 14–8, 3.24 ERA, 1.128 WHIP
  - Possible Catcher: Salvador Perez
- - Framber Valdez (LHP)
  - 13–6, 3.45 ERA, 1.158 WHIP
  - Possible Catcher: Yainer Diaz
- 5:10pm PDT, Guaranteed Rate Field
- Mets
- @
- White Sox
- - Tylor Megill (RHP)
  - 2–5, 4.98 ERA, 1.404 WHIP
  - Probable Catcher: Francisco Álvarez
- - Jonathan Cannon (RHP)
  - 2–8, 4.57 ERA, 1.390 WHIP
  - Probable Catcher: Korey Lee
- 5:10pm PDT, Target Field
- Blue Jays
- @
- Twins
- - Kevin Gausman (RHP)
  - 12–9, 4.10 ERA, 1.222 WHIP
  - Probable Catcher: Alejandro Kirk
- - Pablo Lopez (RHP)
  - 12–8, 4.26 ERA, 1.142 WHIP
  - Possible Catcher: Ryan Jeffers
- 5:40pm PDT, Coors Field
- Orioles
- @
- Rockies
- - Albert Suarez (RHP)
  - 6–4, 3.18 ERA, 1.275 WHIP
  - Probable Catcher: Adley Rutschman
- - Austin Gomber (LHP)
  - 4–9, 4.70 ERA, 1.290 WHIP
  - Possible Catcher: Jacob Stallings
- 6:38pm PDT, Angel Stadium of Anaheim
- Mariners
- @
- Angels
- - George Kirby (RHP)
  - 9–10, 3.48 ERA, 1.114 WHIP
  - Probable Catcher: Cal Raleigh
- - Samuel Aldegheri (LHP)
  - First appearance this season
  - Probable Catcher: Logan O'Hoppe
- 6:40pm PDT, Chase Field
- Dodgers
- @
- Diamondbacks
- - Clayton Kershaw (LHP)
  - 2–2, 3.72 ERA, 1.414 WHIP
  - Probable Catcher: Will Smith
- - Zac Gallen (RHP)
  - 10–6, 3.65 ERA, 1.302 WHIP
  - Possible Catcher: Gabriel Moreno
- 7:15pm PDT, Oracle Park
- Marlins
- @
- Giants
- - Adam Oller (RHP)
  - 1–1, 5.23 ERA, 1.258 WHIP
  - Possible Catcher: Nick Fortes
- - Blake Snell (LHP)
  - 2–3, 3.76 ERA, 1.114 WHIP
  - Possible Catcher: Patrick Bailey

Probable Pitchers

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