Probable Pitchers

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- 8:35am PDT, Fenway Park
- Astros
- @
- Red Sox
- - Framber Valdez (LHP)
  - 11–4, 2.55 ERA, 1.112 WHIP
  - Probable Catcher: Yainer Diaz
- - Lucas Giolito (RHP)
  - 7–2, 3.70 ERA, 1.255 WHIP
  - Probable Catcher: Carlos Narvaez
- 9:10am PDT, George M. Steinbrenner Field
- Dodgers
- @
- Rays
- - Yoshinobu Yamamoto (RHP)
  - 9–7, 2.48 ERA, 1.040 WHIP
  - Probable Catcher: Will Smith
- - Joe Boyle (RHP)
  - 1–1, 2.82 ERA, 0.851 WHIP
  - Possible Catcher: Nick Fortes
- 10:05am PDT, Great American Ball Park
- Braves
- @
- Reds
- - To Be Announced
- - To Be Announced
- 10:35am PDT, Nationals Park
- Brewers
- @
- Nationals
- - Jacob Misiorowski (RHP)
  - 4–1, 2.70 ERA, 0.960 WHIP
  - Probable Catcher: William Contreras
- - Brad Lord (RHP)
  - 2–5, 3.27 ERA, 1.197 WHIP
  - Probable Catcher: Riley Adams
- 10:37am PDT, Rogers Centre
- Royals
- @
- Blue Jays
- - Seth Lugo (RHP)
  - 8–5, 3.03 ERA, 1.129 WHIP
  - Possible Catcher: Salvador Perez
- - Chris Bassitt (RHP)
  - 11–5, 4.24 ERA, 1.341 WHIP
  - Probable Catcher: Alejandro Kirk
- 10:40am PDT, Progressive Field
- Twins
- @
- Guardians
- - José Ureña (RHP)
  - 0–0, 5.40 ERA, 1.527 WHIP
  - Possible Catcher: Ryan Jeffers
- - Joey Cantillo (LHP)
  - 2–1, 4.14 ERA, 1.440 WHIP
  - Possible Catcher: Bo Naylor
- 10:40am PDT, LoanDepot Park
- Yankees
- @
- Marlins
- - Luis Gil (RHP)
  - First appearance this season
  - Probable Catcher: Austin Wells
- - Edward Cabrera (RHP)
  - 4–5, 3.35 ERA, 1.234 WHIP
  - Possible Catcher: Agustin Ramirez
- 10:40am PDT, Citi Field
- Giants
- @
- Mets
- - Carson Whisenhunt (LHP)
  - 0–0, 7.20 ERA, 1.400 WHIP
  - Probable Catcher: Patrick Bailey
- - Frankie Montas (RHP)
  - 3–1, 5.46 ERA, 1.449 WHIP
  - Possible Catcher: Francisco Álvarez
- 11:20am PDT, Wrigley Field
- Orioles
- @
- Cubs
- - Brandon Young (RHP)
  - 0–5, 6.63 ERA, 1.691 WHIP
  - Possible Catcher: Adley Rutschman
- - Colin Rea (RHP)
  - 8–5, 4.25 ERA, 1.302 WHIP
  - Probable Catcher: Carson Kelly
- 12:10pm PDT, Coors Field
- Pirates
- @
- Rockies
- - Mitch Keller (RHP)
  - 4–10, 3.69 ERA, 1.205 WHIP
  - Possible Catcher: Henry Davis
- - Bradley Blalock (RHP)
  - 1–2, 7.09 ERA, 1.636 WHIP
  - Possible Catcher: Hunter Goodman
- 1:05pm PDT, Sutter Health Park
- Diamondbacks
- @
- Athletics
- - Eduardo Rodriguez (LHP)
  - 3–7, 5.83 ERA, 1.651 WHIP
  - Probable Catcher: Jose Herrera
- - Jack Perkins (RHP)
  - 0–1, 2.75 ERA, 0.915 WHIP
  - Probable Catcher: Shea Langeliers
- 1:07pm PDT, Angel Stadium of Anaheim
- White Sox
- @
- Angels
- - Sean Burke (RHP)
  - 4–8, 4.17 ERA, 1.410 WHIP
  - Possible Catcher: Kyle Teel
- - Jack Kochanowicz (RHP)
  - 3–9, 5.66 ERA, 1.601 WHIP
  - Probable Catcher: Logan O'Hoppe
- 1:10pm PDT, Petco Park
- Cardinals
- @
- Padres
- - Andre Pallante (RHP)
  - 6–7, 4.62 ERA, 1.299 WHIP
  - Probable Catcher: Pedro Pagés
- - Dylan Cease (RHP)
  - 3–10, 4.79 ERA, 1.335 WHIP
  - Possible Catcher: Freddy Fermin
- 1:10pm PDT, T-Mobile Park
- Rangers
- @
- Mariners
- - Jacob deGrom (RHP)
  - 10–3, 2.55 ERA, 0.922 WHIP
  - Probable Catcher: Jonah Heim
- - Logan Evans (RHP)
  - 4–4, 4.92 ERA, 1.453 WHIP
  - Probable Catcher: Cal Raleigh
- 4:10pm PDT, Citizens Bank Park
- Tigers
- @
- Phillies
- - Charlie Morton (RHP)
  - 7–8, 5.42 ERA, 1.559 WHIP
  - Probable Catcher: Dillon Dingler
- - Cristopher Sánchez (LHP)
  - 9–3, 2.48 ERA, 1.087 WHIP
  - Probable Catcher: J.T. Realmuto

Probable Pitchers

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